Five alkaloids (akuammidine, akuammine, akuammicine, akuammigine and pseudo-akuammigine) were isolated from the seeds of Akuamma. Akuamma seeds have a rich history across the continent of Africa. The seeds originate from the Akuamma tree (Picralima nitida) and contain “akuammine” as their chief alkaloid. The dried seeds have traditionally been used medicinally throughout West Africa for hundreds of years.
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